Article, 2024

Optimizing and characterizing 4-methyl substituted pyrazol-3-carboxamides leading to the peripheral cannabinoid 1 receptor inverse agonist TM38837

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ISSN 0960-894X, Volume 98, 10.1016/j.bmcl.2023.129572

Contributors

Hogberg, Thomas (Corresponding author) [1] Receveur, Jean-Marie [1] Murray, Anthony [1] Linget, Jean-Michel [1] Norregaard, Pia K. [1] Little, Paul [1] Cooper, Martin [1]

Affiliations

  1. [1] 7TM Pharma AS, Horsholm, Denmark
    2. [NORA names: Other Companies; Private Research; Denmark; Europe, EU; Nordic; OECD]

Abstract

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Keywords

ADME profile, Antiobesity, CB1 antagonists and inverse agonists, Drug design, Liver distribution, Metabolic diseases, Peripheral action

Data Provider: Clarivate

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