Article, Early Access,
Automated enzymatic hydrolysis of urine samples for improved systematic toxicological analysis of drug-facilitated sexual assault cases
Contributors
Skov, K.
0000-0003-1350-9300
(Corresponding author)
[1]
Johansen, S. S.
0000-0002-9555-5134
[1]
Linnet, Kristian
0000-0001-6974-5535
[1]
Nielsen, Marie K. K.
0000-0001-5159-8549
[1]
Affiliations
- [1] Univ Copenhagen, Fac Hlth & Med Sci, Dept Forens Med, Sect Forens Chem, Copenhagen, Denmark [NORA names: KU University of Copenhagen; University; Denmark; Europe, EU; Nordic; OECD]
Abstract
Development and validation of an UHPLC-MS/MS screening method covering 144 drugs and metabolites relevant to drug-faciliated sexual assaults. The method included an automated enzymatic hydrolysis for an improved systemtatic toxicological analysis of DFSA cases.image
Keywords
DFSA,
STA,
recombinant enzymes,
sample preparation,
urine
