open access publication

Review, 2024

Adherence to newer second-line oral antidiabetic drugs among people with type 2 diabetes-A systematic review

PHARMACOLOGY RESEARCH & PERSPECTIVES, ISSN 2052-1707, 2052-1707, Volume 12, 2, 10.1002/prp2.1185

Contributors

Holdt-Caspersen, Nynne Sophie (Corresponding author) [1] [2] Dethlefsen, Claus [1] [2] Vestergaard, P. [1] [3] Hejlesen, Ole 0000-0003-3578-8750 [1] Hangaard, S. [1] [3] Jensen, M. H. 0000-0002-6649-8644 [1] [2]

Affiliations

  1. [1] Aalborg Univ Hosp, Dept Endocrinol, Aalborg, Denmark
    2. [NORA names: AAU Aalborg University; University; Denmark; Europe, EU; Nordic; OECD];
  2. [2] Novo Nordisk, Dept Biostat, Aalborg, Denmark
    3. [NORA names: Novo Nordisk; Private Research; Denmark; Europe, EU; Nordic; OECD];
  3. [3] Aalborg Univ Hosp, Dept Endocrinol, Aalborg, Denmark
    4. [NORA names: North Denmark Region; Hospital; Denmark; Europe, EU; Nordic; OECD]

Abstract

The adherence to newer second-line oral antidiabetic drugs among people with type 2 diabetes was investigated in this study. A systematic literature search was performed in six databases. A total of 14948 records was retrieved from the databases of which 7 articles were included. The reported medication possession ratio (MPR) and treatment discontinuation was extracted from the articles, and these findings were visualised in figures and summarized in a narrative synthesis. The findings indicate that the adherence to the newer second-line OADs may be better than that of older OADs, but a study directly comparing older and newer OADs should be performed to verify this.image

Keywords

adherence, oral antidiabetic drug, review, type 2 diabetes

Data Provider: Clarivate

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