Article, Early Access, 2024

Raman spectroscopy and one-dimensional convolutional neural network modeling as a real-time monitoring tool for in vitro transaminase-catalyzed synthesis of a pharmaceutically relevant amine precursor

BIOTECHNOLOGY PROGRESS, ISSN 8756-7938, 10.1002/btpr.3444

Contributors

Madsen, Julie osterby [1] [2] Topalian, Sebastian Olivier Nymann [1] Jacobsen, Mikkel Fog [3] Skovby, Tommy [3] Gernaey, Krist V. [1] Myerson, Allan S. [2] Woodley, John (Corresponding author) [1]

Affiliations

  1. [1] Tech Univ Denmark, Dept Chem & Biochem Engn, DK-2800 Lyngby, Denmark
    2. [NORA names: DTU Technical University of Denmark; University; Denmark; Europe, EU; Nordic; OECD];
  2. [2] MIT, Dept Chem Engn, Cambridge, MA USA
    3. [NORA names: United States; America, North; OECD];
  3. [3] H Lundbeck A S, Chem Prod Dev, Nykobing Sjaelland, Denmark
    4. [NORA names: Lundbeck; Private Research; Denmark; Europe, EU; Nordic; OECD]

Abstract

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Keywords

Raman spectroscopy, biocatalysis, chemometrics, real-time monitoring, transaminase

Data Provider: Clarivate

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