open access publication

Article, 2024

Are Gamers Prone to eThrombosis during Long Gaming Sessions?

LIFE-BASEL, Volume 14, 4, 10.3390/life14040525

Contributors

Krarup, Kasper B. 0000-0003-3548-4335 [1] [2] [3] Krarup, Henrik B. [2] [3] Mork, M. [2] [3] Lundbye-Christensen, Soren [2] Handberg, A. 0000-0001-5719-203X [2] [3] Nguyen, Hien T. T. [2] [3] Pedersen, Inge Sokilde [2] [3] Kristensen, Soren R. (Corresponding author) [2] [3]

Affiliations

  1. [1] Reg Hosp North Jutland, Sports Med Ctr, DK-9900 Frederikshavn, Denmark
  2. [NORA names: North Denmark Region; Hospital; Denmark; Europe, EU; Nordic; OECD];
  3. [2] Aalborg Univ Hosp, Dept Clin Biochem, DK-9000 Aalborg, Denmark
  4. [NORA names: AAU Aalborg University; University; Denmark; Europe, EU; Nordic; OECD];
  5. [3] Aalborg Univ Hosp, Dept Clin Biochem, DK-9000 Aalborg, Denmark
  6. [NORA names: North Denmark Region; Hospital; Denmark; Europe, EU; Nordic; OECD]

Abstract

During the last two decades, several cases of venous thrombosis (VTE) after a prolonged period at a computer have been described, denominated as "eThrombosis". Video gaming on a computer has become very popular and can be a social activity where several players gather to play against each other or in a virtual environment for several days ("LAN (i.e., Local Area Network) parties") where the participants are sedentary and consuming calorie-rich food items. The aim of this study was to investigate potential coagulation activation during a 42 h LAN party. Nine male gamers volunteered for the LAN party. Citrated blood was sampled before and every 6 h, and plasma was analyzed for thrombin generation, thrombin-antithrombin complexes (TAT), prothrombin fragment 1 + 2 (F1 + 2), and D-dimer. Thrombin generation increased slightly but not significantly during the LAN party, whereas the coagulation activation markers were unchanged. These results do not indicate that the coagulation system is activated significantly during 42 h of gaming with minimal physical activity. Although increased activity cannot be excluded, it does not directly indicate a risk of VTE in general.

Keywords

D-dimer, F1+2, LAN party, TAT, coagulation activation, eThrombosis, thrombin generation

Data Provider: Clarivate